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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Elastin like polypeptides ： ウィキペディア英語版 Elastin like polypeptides Elastin-like polypeptides (ELPs) are artificial protein polymers composed of pentapeptide Val–Pro–Gly–Xaa–Gly. In this motif Xaa (so called "guest residue") can be any amino acid except proline. ELP are able to undergo reversible phase transition induced by pH, temperature or ionic strength. This behaviour is very useful and depends on transition temperature (Tt) of ELP molecule. These polymers are soluble at a temperature below the Tt, but insoluble when the temperature exceeds Tt. ELP are useful in medicine (e.g. cancer therapy, regenerative medicine) or recombinant proteins purification. ==References== *T. Kowalczyk, K. Hnatuszko-Konka, A. Gerszberg, AK. Kononowicz. Elastin-like polypeptides as a promising family of genetically-engineered protein based polymers. „World J Microbiol Biotechnol”. 30 (8), s. 2141-2152, 2014. DOI: 10.1007/s11274-014-1649-5. PMID 24699809. PMCID: PMC4072924. *A. Valiaev, DW. Lim, S. Schmidler, RL. Clark et al. Hydration and conformational mechanics of single, end-tethered elastin-like polypeptides. „J Am Chem Soc”. 130 (33), s. 10939-10946, 2008. DOI: 10.1021/ja800502h. PMID 18646848. PMCID: PMC2736882. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Elastin like polypeptides」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.